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KMID : 0386419990120041071
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Journal of the Korean Fracture Society
1999 Volume.12 No. 4 p.1071 ~ p.1076
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Autogenous bone marrow injection for the treatment of delayed union of the long bone
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Sung Jin-Hyung
Ryu Jae-Duk
Kim Weon-Yoo
Han Chang-Hwan
Uhm Eui-Young
Kim Jin-Young
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Abstract
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It is known that the Salter-Harris type I and II fractures of the distal tibial epiphysis usuallyFor resolving problems of delayed union and non-union of long bones, many efforts was madesuch as autogenous graft, allogenic or artificial bone graft and electrical stimulation, but therewere many complications and not sufncient fracture healing process. The purpose of this studywas to investigate the effect of autograft with bone marrow on the repair or bone formation ofdelayed union by the serial radiogram and clinical examination. We evaluated thirty ninepatients which had been treated for long bone fracture, to whom bone marrow injection wasmade between 3 months and 13 months after adequate fixation(average.4.8months). After bonemarrow injection, clinical follow up period was from 15 months to 35 months(average26.7months). The age distribution was from 18 years to 84 years(average 42). A total of 100-150cc of marrow was injected at the nonunion site immediately after aspiration under the C-arm.Of 39 cases, there were improved bone healing process of 30 cases(77%) by radiographicallyand clinically, Of 9 cases without improvement, 5 cases were due to loosening of externalfixator, 2 cases was due to chronic osteomyelitis and other 2 cases was unknown origin. Noserious complications were observed other than no improvement. Although percutaneous bonemarrow injection does not promote healing more rapidly than would standard operative bonegrafting, it has many distinct advantages over the latter. It is safe, easy, and time saving. It iseconomical and involves minimal trauma. It can be done under local anesthesia and avoids therisks of general anesthesia, infection and surgery. It can be done in cases which are not fit foropen bone grafting because of poor condition of the skin.
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KEYWORD
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long bone, delayed union, bone marrow injection
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